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The nucleotide sequence of a blaKPC-2-harboring plasmid (pKPCAPSS) from Klebsiella pneumoniae ST273 isolated in Saint Petersburg, Russia, from a patient with history of recent travel to Vietnam is presented. This 127,970-bp plasmid possessed both IncFII and IncR replicons. blaKPC-2 was localized on a hypothetical mobile element. This element was flanked by 38-bp inverted Tn3 repeats and included a Tn3-specific transposase gene, macrolide resistance operon (mphA-mrx-mphR), and a fragment of blaTEM with unique polymorphisms. © 2017 American Society for Microbiology. All Rights Reserved.

Genetic environment of the blaKPC-2 gene in a Klebsiella pneumoniae isolate that may have been imported to Russia from Southeast Asia / Ageevets, V; Sopova, J; Lazareva, I; Malakhova, M; Ilina, E; Kostryukova, E; Babenko, V; Carattoli, A.; Lobzin, Y; Uskov, A; Sidorenko, S.. - In: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. - ISSN 0066-4804. - 61:2(2017). [10.1128/AAC.01856-16]

Genetic environment of the blaKPC-2 gene in a Klebsiella pneumoniae isolate that may have been imported to Russia from Southeast Asia

Carattoli A.;
2017

Abstract

The nucleotide sequence of a blaKPC-2-harboring plasmid (pKPCAPSS) from Klebsiella pneumoniae ST273 isolated in Saint Petersburg, Russia, from a patient with history of recent travel to Vietnam is presented. This 127,970-bp plasmid possessed both IncFII and IncR replicons. blaKPC-2 was localized on a hypothetical mobile element. This element was flanked by 38-bp inverted Tn3 repeats and included a Tn3-specific transposase gene, macrolide resistance operon (mphA-mrx-mphR), and a fragment of blaTEM with unique polymorphisms. © 2017 American Society for Microbiology. All Rights Reserved.
2017
Amikacin; ampicillin; aztreonam; biapenem; cefepime; cefotaxime; ceftazidime; chloramphenicol; ciprofloxacin; cotrimoxazole; ertapenem; fosfomycin; gentamicin; imipenem; meropenem; polymyxin B; antiinfective agent; beta lactamase; beta-lactamase KPC-2, Klebsiella pneumoniae; macrolide; transposase, amplicon; antibiotic resistance; Article; bacterial genetics; case report; Escherichia coli; female; human; Klebsiella pneumoniae; multilocus sequence typing; nonhuman; nucleotide sequence; pelvic inflammatory disease; priority journal; Russian Federation; Sanger sequencing; single nucleotide polymorphism; Southeast Asia; whole genome sequencing; drug effects; genetics; isolation and purification; Klebsiella infection; Klebsiella pneumoniae; microbial sensitivity test; microbiology; operon; plasmid; Viet Nam, Anti-Bacterial Agents; Asia, Southeastern; beta-Lactamases; Drug Resistance, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Macrolides; Microbial Sensitivity Tests; Operon; Plasmids; Russia; Transposases; Vietnam
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Genetic environment of the blaKPC-2 gene in a Klebsiella pneumoniae isolate that may have been imported to Russia from Southeast Asia / Ageevets, V; Sopova, J; Lazareva, I; Malakhova, M; Ilina, E; Kostryukova, E; Babenko, V; Carattoli, A.; Lobzin, Y; Uskov, A; Sidorenko, S.. - In: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. - ISSN 0066-4804. - 61:2(2017). [10.1128/AAC.01856-16]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1284236
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